Synthesis, Characterization, and Antibacterial Activity of Ni-Substituted Krebs-type Sandwich-Tungstobismuthates Functionalized with Amino Acids

Autor(en)
Morteza Rafieeshad, Nadiia I. Gumerova, Elias Tanuhadi, Gerald Giester, Hana Čipčić-Paljetak, Donatella Verbanac, Annette Rompel
Abstrakt

Four new Ni-substituted Krebs-type sandwich-tungstobismuthates, K4Ni2[{Ni(β-ala)(H2O)2}2{Ni(H2O)}2{Ni(H2O)(η2-β-ala)}2(B-β-BiW9O33)2]·49H2O {(β-ala)4(Ni3)2(BiW9)2}, K3.5Na6.5[{Ni(η3-L-asp)}2(WO2)2(B-β-BiW9O33)2]·36H2O·L-asp {(L-asp)2(NiW)2(BiW9)2}, K4Na6[{Ni(gly)(H2O)2}2(WO2)2(B-β-BiW9O33)2]·86H2O {(gly)2(NiW)2(BiW9)2}, and K2Na8[{Ni(η2-serinol) (H2O)}2{Ni(H2O)2}2(B-β-BiW9O33)2]·42H2O {(serinol)2Ni4(BiW9)2} have been synthesized by one-pot solution methods. All compounds have been characterized in the solid state by single-crystal X-ray diffraction (SXRD), powder X-ray diffraction (PXRD), elemental and thermogravimetric analyses, and infrared spectroscopy (IR), as well as by UV-vis spectroscopy in solution. The antibacterial activity of all compounds was studied against four bacterial strains by the determination of the minimum inhibitory concentration (MIC). The results showed that only {(β-ala)4(Ni3)2(BiW9)2} demonstrates antibacterial activity (MIC is in the range from 8 to 256 μg/mL) compared to three other Ni-Krebs sandwiches.

Organisation(en)
Institut für Biophysikalische Chemie, Institut für Mineralogie und Kristallographie
Externe Organisation(en)
University of Zagreb
Journal
Inorganic Chemistry
Band
62
Seiten
9484-9490
Anzahl der Seiten
7
ISSN
0020-1669
DOI
https://doi.org/10.1021/acs.inorgchem.3c00747
Publikationsdatum
06-2023
Peer-reviewed
Ja
ÖFOS 2012
106002 Biochemie, 106006 Biophysik, 104003 Anorganische Chemie, 104017 Physikalische Chemie
ASJC Scopus Sachgebiete
Physical and Theoretical Chemistry, Inorganic Chemistry
Link zum Portal
https://ucrisportal.univie.ac.at/de/publications/synthesis-characterization-and-antibacterial-activity-of-nisubstituted-krebstype-sandwichtungstobismuthates-functionalized-with-amino-acids(61d71bda-c524-4e67-b470-7f8c04cb9774).html