Supramolecular recognition and structural elucidation of inclusion complexes of an achiral carbene precursor in ß- and permethylated ß-cyclodextrin
- Autor(en)
- Jean-Luc Mieusset, Daniel Krois, Mirjana Pacar, Lothar Brecker, Gerald Giester, Udo H. Brinker
- Abstrakt
Equation presented. Inclusion of achiral carbene precursor endo-8-azibicyclo[3.2.1]octan-3-ol (1) in chiral ß-cyclodextrin (7-Cy) and tri-O-methyl-ß-cyclodextrin (TRIMEB) leads to 1:1 complexes 1@7-Cy and 1@TRIMEB, respectively. The combined methods of induced circular dichroism, NMR spectroscopy, and X-ray structure determination were employed for the first time for structural elucidation of the complexes in solution and the solid state. Significantly different orientations of 1 were observed. Compared with 1@7-Cy, 1@TRIMEB exhibits a different guest orientation and an association constant one-twentieth lower.
- Organisation(en)
- Institut für Organische Chemie, Institut für Mineralogie und Kristallographie
- Journal
- Organic Letters
- Band
- 6
- Seiten
- 1967-1970
- Anzahl der Seiten
- 4
- ISSN
- 1523-7060
- Publikationsdatum
- 2004
- Peer-reviewed
- Ja
- ÖFOS 2012
- 1051 Geologie, Mineralogie
- Link zum Portal
- https://ucrisportal.univie.ac.at/de/publications/8956ab68-9920-4f1c-b3a2-088f08fb9102