Synthesis of thieno[2,3-b]pyrazines via an acylation-deacylation process of 3,4-dihydro precursors
- Autor(en)
- Thomas Erker, Karin Trinkl, Franz Pertlik
- Abstrakt
In the first step 3, 4-dihydrothieno[2,3-b]pyrazines (1, 2 and 4) were N-acylated by the acyl chlorides followed by a deacylation process mediated by triethylamine to give thieno[2,3-b]pyrazines. In a final rection the excess of the appropriate acyl chlorides react with the free hydroxy residue to afford compounds (15, 16 or 17).
- Organisation(en)
- Institut für Mineralogie und Kristallographie
- Externe Organisation(en)
- Universität Wien
- Journal
- Heterocycles
- Band
- 60
- Seiten
- 337-344
- Anzahl der Seiten
- 8
- ISSN
- 0385-5414
- DOI
- https://doi.org/10.3987/COM-02-9638
- Publikationsdatum
- 2003
- Peer-reviewed
- Ja
- ÖFOS 2012
- 3012 Pharmazie, Pharmakologie, Toxikologie
- Link zum Portal
- https://ucrisportal.univie.ac.at/de/publications/f4612285-eb1b-4bba-bcb3-300e702d8eaa