Synthesis, Characterization, and Antibacterial Activity of Ni-Substituted Krebs-type Sandwich-Tungstobismuthates Functionalized with Amino Acids

Author(s)
Morteza Rafieeshad, Nadiia I. Gumerova, Elias Tanuhadi, Gerald Giester, Hana Čipčić-Paljetak, Donatella Verbanac, Annette Rompel
Abstract

Four new Ni-substituted Krebs-type sandwich-tungstobismuthates, K4Ni2[{Ni(β-ala)(H2O)2}2{Ni(H2O)}2{Ni(H2O)(η2-β-ala)}2(B-β-BiW9O33)2]·49H2O {(β-ala)4(Ni3)2(BiW9)2}, K3.5Na6.5[{Ni(η3-L-asp)}2(WO2)2(B-β-BiW9O33)2]·36H2O·L-asp {(L-asp)2(NiW)2(BiW9)2}, K4Na6[{Ni(gly)(H2O)2}2(WO2)2(B-β-BiW9O33)2]·86H2O {(gly)2(NiW)2(BiW9)2}, and K2Na8[{Ni(η2-serinol) (H2O)}2{Ni(H2O)2}2(B-β-BiW9O33)2]·42H2O {(serinol)2Ni4(BiW9)2} have been synthesized by one-pot solution methods. All compounds have been characterized in the solid state by single-crystal X-ray diffraction (SXRD), powder X-ray diffraction (PXRD), elemental and thermogravimetric analyses, and infrared spectroscopy (IR), as well as by UV-vis spectroscopy in solution. The antibacterial activity of all compounds was studied against four bacterial strains by the determination of the minimum inhibitory concentration (MIC). The results showed that only {(β-ala)4(Ni3)2(BiW9)2} demonstrates antibacterial activity (MIC is in the range from 8 to 256 μg/mL) compared to three other Ni-Krebs sandwiches.

Organisation(s)
Department of Biophysical Chemistry, Department of Mineralogy and Crystallography
External organisation(s)
University of Zagreb
Journal
Inorganic Chemistry
Volume
62
Pages
9484-9490
No. of pages
7
ISSN
0020-1669
DOI
https://doi.org/10.1021/acs.inorgchem.3c00747
Publication date
06-2023
Peer reviewed
Yes
Austrian Fields of Science 2012
106002 Biochemistry, 106006 Biophysics, 104003 Inorganic chemistry, 104017 Physical chemistry
ASJC Scopus subject areas
Physical and Theoretical Chemistry, Inorganic Chemistry
Portal url
https://ucrisportal.univie.ac.at/en/publications/61d71bda-c524-4e67-b470-7f8c04cb9774