Synthesis of thieno[2,3-b]pyrazines via an acylation-deacylation process of 3,4-dihydro precursors
- Author(s)
- Thomas Erker, Karin Trinkl, Franz Pertlik
- Abstract
In the first step 3, 4-dihydrothieno[2,3-b]pyrazines (1, 2 and 4) were N-acylated by the acyl chlorides followed by a deacylation process mediated by triethylamine to give thieno[2,3-b]pyrazines. In a final rection the excess of the appropriate acyl chlorides react with the free hydroxy residue to afford compounds (15, 16 or 17).
- Organisation(s)
- Department of Mineralogy and Crystallography
- External organisation(s)
- University of Vienna
- Journal
- Heterocycles
- Volume
- 60
- Pages
- 337-344
- No. of pages
- 8
- ISSN
- 0385-5414
- DOI
- https://doi.org/10.3987/COM-02-9638
- Publication date
- 2003
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 3012 Pharmacy, Pharmacology, Toxicology
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/f4612285-eb1b-4bba-bcb3-300e702d8eaa